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Could a rise in cases of Pyloric stenosis be linked to erythromycin?

Spitting up is common in babies, but a few infants can hardly keep anything down. When the valve at the bottom of the stomach gets too tight, we call it pyloric stenosis, a condition that affects about 0.3% of babies.

The Centers for Disease Control and Prevention (CDC) reported a cluster of cases in 1999 in babies who had received erythromycin. I’ve also seen more cases of pyloric stenosis in 1999 than I usually do, (even though I am practicing less)- and these babies had not received erythromycin. Coincidence? Is pyloric stenosis really increasing? If so, why? If this has affected you, please let me know about your experience. One of the great benefits of the Internet is the acceleration of learning through shared knowledge.

Published on: February 02, 2000
About the Author

Alan Greene MD

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Dr. Greene is a practicing physician, author, national and international TEDx speaker, and global health advocate. He is a graduate of Princeton University and University of California San Francisco.
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