Will my Baby outgrow Gastroesophageal Reflux?


My daughter has reflux and is on Cisapride and still has some reflux. It's not affecting her growth. My pediatrician put her on it because of a bad cough. How long does reflux last? When will she grow out of it?
Jackie Campbell - Office Coordinator - Arkansas Children's Hospital - Little Rock, Arkansas

Dr. Greene's Answer

A baby who spits up all the time…an adult with heartburn…a child who won’t gain weight…an unhappy toddler…a chronic coughwheezing…recurrent pneumonia…an infant who cries and cries…any one of these may be the only symptom of a common condition called gastroesophageal reflux.

Between the esophagus and the stomach is a portal called the lower esophageal sphincter (LES). Normally, when someone swallows, the food travels down the esophagus, the sphincter relaxes, and food is permitted to enter the stomach where a pool of acid awaits to continue digesting the food. The sphincter then closes tight.

When the sphincter does not remain tightly closed, the acid and the food slosh back up into the esophagus. This is what is meant by reflux. These reflux stomach contents can burn the lining of the esophagus and irritate the lungs. A small amount of reflux immediately following meals is common in healthy adults and causes no problems. Swallowing saliva to wash away the acid protects the vulnerable walls of the esophagus.

In most newborns the lower esophageal sphincter is relatively lax. Thus, frequent spitting up is common in infants. This is called physiologic reflux. These are normal, happy babies who eat well, gain weight, and who have no other symptoms. Still, this spitting up is often upsetting to parents. Physiologic reflux can also be quite inconvenient in that parents frequently must change clothes — theirs and the child’s. One of my sons was a big spitter-upper.

Over time, the lower esophageal sphincter becomes more competent; children eat more solid food; they assume a more upright posture. The spitting up diminishes. In most cases the spitting up resolves without treatment by about 18 months of age. If it persists beyond age 2, there is generally not much improvement until at least age 4. Over the next few years a number of children outgrow the condition, but the closer they get to puberty with reflux, the more likely they are to have reflux as adults — unless corrected.

When reflux lasts beyond about 18 months, or when it is associated with other symptoms at any age, it should be evaluated. These other symptoms might include poor weight gain, heartburn, irritability (especially after eating or while lying down), bad breath, excessive cavities, wheezing, chronic cough, pain with eating, or recurrent pneumonias. A child might have any or all of these symptoms, but not actually spit up, if the stomach contents are re-swallowed.

Persistent or symptomatic reflux is called pathologic reflux. About two-thirds of children with pathologic reflux have have poor weight gain (I’m glad your daughter doesn’t). Medical treatment for this is usually quite effective. It might include changing feeding and posture habits. Medications such as cisapride (which has been pulled off the market) or metoclopramide can help speed the emptying of stomach contents into the intestine. There are medications that work to reduce stomach acid. Whether a child’s symptom, such as your daughter’s cough, responds well to treatment depends largely on whether the cough is actually a response to the reflux.

If pathologic reflux persists despite prolonged medical therapy, a surgical procedure called a Nissen fundoplication is sometimes performed. This uses folds of the stomach to tighten the lower esophageal sphincter and it is quite effective. I hope that your daughter will grow out of this condition in the near future, but if she doesn’t, take comfort in knowing that there is excellent medical treatment available.

Last medical review on: February 03, 2008
About the Author
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Dr. Greene is a practicing physician, author, national and international TEDx speaker, and global health advocate. He is a graduate of Princeton University and University of California San Francisco.
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My lo is 3.5 months old and weighs only 8 lbs 10oz. He was ebf for the first three months. He weighed 6.8 at birth and when we left the hospital he weighed 5lbs 15 oz. We started formula and breastmilk and in 2 weeks he only gained 4oz. He does spit up a lot, his pediatrician requested labs to be drawn and wants to send him to a specialist. He did diagnose him with failure to thrive.