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Fast Fact
Most bacteria and viruses that cause infections in humans thrive best at 98.6 degrees F (37C). Raising the temperature a few degrees can give the body the winning edge. In addition, a fever activates the body's immune system, accelerating the production of white blood cells, antibodies, and many other infection-fighting agents.
Brain damage from a fever will not occur unless the fever is over 107.6 degrees F (42C) for an extended period of time.
Untreated fevers caused by infection will seldom go over 105 degrees unless the child is overdressed or trapped in a hot place. In a neurologically normal child, the brain's thermostat will stop the fever from climbing above 106 degrees F.
· About 4% of children will sometimes have seizures with fever. These febrile seizures are caused by rapid increase in temperature, not by the height of the temperature. Once a child already has a high fever and a febrile seizure, a febrile seizure is unlikely to reoccur with the current illness. In any event, typical febrile seizures are over in moments with no lasting consequences.
While 98.6 degrees F is considered the normal core body temperature, this value varies between individuals and throughout the day. The daily variation is minimal in children less than six months of age, about 1 degree in children 6 months to 2 years old, and gradually increases to 2 degrees per day by age six. A person's baseline temperature is usually highest in the evening. Body temperature, especially in children, is normally raised by physical activity, strong emotion, eating, heavy clothing, elevated room temperature, and elevated humidity. Rectal temperatures below 100.4 degrees F (38C) may be entirely normal (no fever). A rectal temperature of 100.4 or above should be considered a fever. Lower values might be a fever, depending on the child.
A fever does not necessarily need to be treated. If a child is playful and comfortable, drinking plenty of fluids, and able to sleep, fever treatment is not likely to be helpful.
Steps should be taken to lower a fever if the child is uncomfortable, vomiting, dehydrated, or having difficulty sleeping. The goal is to bring the temperature between about 100 and 102 degrees F -- not to eliminate the fever.
When trying to reduce a fever, first remove excess clothing or blankets. The environment should be comfortably cool (one layer of light weight clothing, and one lightweight blanket to sleep).
Two medicines are useful for reducing fever in children: acetaminophen (Tylenol) and ibuprofen (Children's Advil or Motrin). Acetaminophen is given every 4-6 hours, and works by turning down the brain's thermostat. Don't use under three months of age without first having the child examined by a physician. Ibuprofen is given every 6-8 hours, and helps fight the inflammation at the source of the fever. It is not approved for children under 6 months. Both medicines may be given for stubborn fevers, but be very careful about using the correct dose of each.
A lukewarm bath or sponge bath may help cool a febrile child (after medication is given -- otherwise the temperature bounces right back up). Cold baths or alcohol rubs cool the skin, but often make the situation worse by causing shivering, which raises the core body temperature.
Fever is a signal that something is going on in your child. Usually this is a minor illness, but it can be a serious infection, such as meningitis. Any child less than 90 days old with a fever should be examined by a physician right away, to rule out a serious infection (unless there was a DPT shot in the previous 24 hours). Children of any age who have a fever 104 degrees or more should also be seen, unless the fever comes down readily with treatment and the child is comfortable. Any child who has a fever and is very irritable, ill appearing, confused, has difficulty breathing, has a stiff neck, won't move an arm or leg, or who has a seizure should also be seen right away.
Even without the above symptoms, children under 6 months of age with a fever should be examined by a physician within 24 hours (again unless they just had a DPT), since they may have some infection that needs to be treated. Older children with a fever (6 to 24 months old) who are acting well and have no other symptoms should be seen if the fever lasts >48 hours (or >72 hours if they do have minor cold or flu symptoms).
Why do some premature children born under chronic stress get to have more chances of surviving compared with those who are born free of stress? Why do intrauterine steroids stimulate surfactant production?
Physician - Philippines
"Why" questions are often the most interesting and the most rewarding. They are also among the most difficult to answer.
Your observations are correct -- premature children who have been subjected to stress tend to have better survival and less lung disease, compared to those premature babies who are born without a preceding stressful period. Your observation that the administration of steroids to mothers in pre-term labor tends to speed fetal lung maturity is also correct. But, why should these things be?
When a child is born, the lungs change from fluid-filled sacs to air-breathing organs. This transition is an important part of birth. During labor, mechanical forces help to squeeze out fluid from the lungs. Steroid hormones secreted by the mother during labor also help ready the baby for the transitions of the first day of life. The body normally secretes corticosteroids in response to stressful situations -- including labor. These hormones affect every cell of the body, preparing them to meet the stressful situation.
A child who is born before the normal gestational age has not yet finished in-utero development. If the delivery is abrupt, a partially developed baby is born. If, on the other hand, the baby has been subjected to a period of chronic stress lasting for at least several days before the birth takes place, the baby "realizes" that she may be delivered too soon. The most vital steps of maturation (notably regarding the lungs) are rapidly accelerated. The mechanism for this is the release of stress hormones. This situation can be mimicked when a delivery is imminent by treating the mother with a steroid such as betamethasone. This has been proven to accelerate lung maturation, including the production of surfactant (a "soapy" film that coats the inside of the lung, reduces surface tension, and makes breathing easier).
The design of our bodies is truly fabulous. When the normal situation (for example normal gestational period) doesn't pertain, self-correcting, healing mechanisms are in place to try to get us back on track.
One way to think about steroids, or stress hormones (which have many effects throughout the body), are as agents that tend to mature us. In premature infants, the stress tends to make them ready to face the world a little sooner. In children who are chronically stressed or treated with steroids, a common side effect is premature closure of the growth plates of their bones -- they reach the end of their growth more quickly. Adults who are stressed or who are treated with steroid hormones tend to reach the next level of maturity, (including osteoporosis, cataracts, diabetes, heart disease, and death) more quickly.
Thus some degree of stress, of challenge, is necessary to keep us moving forward and growing throughout our lives, but as you can see, excess stress is destructive. Brief periods of great stress help to move us through crises, but chronic excess stress is unhealthy. Live in a zone of moderate challenge.
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