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Fast Fact
Trisomy 13 (also called Patau Syndrome) occurs in up to 1 out of 5,000 newborns (Smith's Recognizable Patterns of Human Malformation, Saunders 1988).
The 13th chromosome contains blueprints that direct a baby's development in the early weeks following conception. When a child has an extra 13th chromosome (three copies, instead of two), as is the case in trisomy 13, the genetic messages are confused and contradictory. This results in multiple significant defects in major organ systems.
The brain is often the most severely affected. Most children with trisomy 13 also have some kind of heart defect. It's not unusual for these children to be born blind, deaf, and with no sense of smell. Children with trisomy 13 may also have abnormalities in the shape of their lips, eyes, ears, fingers, toes, and bones.
Trisomy 13 was first described in 1657, but four hundred fifty years of medical knowledge have not improved the outlook for children born with this syndrome.
Most babies who are conceived with trisomy 13 die early in gestation. Of the babies who live to be born, about 44 % die within the first month and 69% die by six months. Only 18 percent reach their first birthdays -- and these children tend to have severe mental defects and seizures (Smith's Recognizable Patterns of Human Malformation, Saunders 1988).
A blood test, called the AFP (alphafetoprotein) or triple screen, may help a pregnant woman find out her baby’s risk of several diseases, including Trisomy 21 (Down Syndrome) and Trisomy 13, though it can not give a definite answer.
Trisomy 13 is often detectable on ultrasound as early as 10 weeks. Chorionic villous sampling can detect trisomy 13 by 12 weeks. Amniocentesis, usually performed after 16 weeks gestation, can give a definite answer if any question still remains.
A trisomy 13 translocation is not associated with mom's age, but is a hereditary chromosome problem. The risk of recurrence in some types of (balanced) translocations can be quite high.
Some 2,500 people were tested in the largest survey ever to see if the pesticides and other chemicals polluting our environment are also polluting our bodies.
The Story
Some 2,500 people were tested in the largest survey ever to see if the pesticides and other chemicals polluting our environment are also polluting our bodies. Levels of 116 chemicals found in food, soil, water, air, or dust were measured to see if they were also in people’s bodies (for 89 of them, this was the first survey). This huge undertaking shows the staggering amount of chemicals now in our bodies. It also confirms the results of previous smaller studies: children are at greater risk for higher exposure than are adults. Organophosphate pesticides, for instance, were found at about twice the levels in children’s bodies, compared to adults (and remember, even at the same levels children would more likely be harmed).
Also of note, DDT continues to be detected in people in the U.S., even though its use was banned in 1973. The adverse effects of DDT are well-documented. It is particularly devastating to children. In this study, DDT was found in today’s children – born long after the ban! The CDC states, “Food is the primary pathway of DDT exposure for the general population.” Continued exposure “may be from persisting DDT/DDE in the environment or DDT residues in food.” Also, food imported from other countries may still be grown with DDT.
Food is the primary pathway for many of the chemicals in the CDC report. Organic foods are grown without pesticides or other toxic chemicals that contaminate our soil, water or food – or our children.
Notes
Work was done at the CDC’s Environmental Health Laboratory. They tested the blood and urine of selected participants in the National Health and Nutrition Examination Survey (NHANES) conducted by the CDC’s National Center for Health Statistics.
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