Could a rise in cases of Pyloric stenosis be linked to erythromycin?

Could a rise in cases of Pyloric stenosis be linked to erythromycin?

Spitting up is common in babies, but a few infants can hardly keep anything down. When the valve at the bottom of the stomach gets too tight, we call it pyloric stenosis, a condition that affects about 0.3% of babies.

The Centers for Disease Control and Prevention (CDC) reported a cluster of cases in 1999 in babies who had received erythromycin. I’ve also seen more cases of pyloric stenosis in 1999 than I usually do, (even though I am practicing less)- and these babies had not received erythromycin. Coincidence? Is pyloric stenosis really increasing? If so, why? If this has affected you, please let me know about your experience. One of the great benefits of the Internet is the acceleration of learning through shared knowledge.

Dr. Alan Greene

Dr. Greene is the founder of (cited by the AMA as “the pioneer physician Web site”), a practicing pediatrician, father of four, & author of Raising Baby Green & Feeding Baby Green. He appears frequently in the media including such venues as the The New York Times, the TODAY Show, Good Morning America, & the Dr. Oz Show.

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