Diphtheria is a very serious bacterial disease that can make a person unable to breathe, cause paralysis, or even heart failure.
About 10% of the people who get diphtheria die from it. Before the DPT shot was introduced, 17,000 children died in a single year in the United States alone in a diphtheria epidemic.
Over the last several years, only a very few cases of diphtheria have been reported in the United States. In 1988 there were zero cases. This is primarily because most children have had shots to protect them.
Tetanus, also called lockjaw, is caused by a bacterium that is common in the soil. When this germ gets into an open cut or wound, an unprotected person can contract tetanus, which creates serious muscle spasms that can be strong enough to snap the spine.
Even with modern medical care, about 30% of the people who get tetanus die from the disease.
Tetanus was once very widespread, but since 1975 only 50 to 100 cases have been reported each year in the United States.
Pertussis, more commonly known as whooping cough, can either be a very mild or a very serious disease. It is extremely contagious. It causes repeated spells of coughing that can make it difficult to eat, drink, or breathe.
The number of pertussis cases has climbed in recent years. In 2004, there were 25,827 reported cases.
In most adults, pertussis is very mild. Almost 20% of all adults with chronic coughs may have pertussis that they mistake for allergies or a cold.
In young children it is more severe. It causes repeated spells of coughing that can make it difficult to eat, drink, or breathe.
Babies under 1 year old are most affected. About 1 out of every 200 babies who get pertussis will die of it. Another 1 out of every 200 will have lifetime brain damage. As many as 2% will have seizures, 22% will get pneumonia, and many (even in this modern era of reduced hospitalization) will be sick enough to be hospitalized.
Moderate reactions to the DTaP vaccine occur in 0.1% or less of children and include ongoing crying (for three hours or more), a high fever (up to 105 degrees F), and an unusual, high-pitched crying.
Less than 0.06% of children will have a febrile seizure or a period of shock-collapse, where they become pale and limp for a short period. While these side effects are certainly disturbing, all of the above problems are temporary and have never been demonstrated to create a long-term problem of any kind.
Severe problems from the DTaP immunization happen very rarely (less than 1 in a million doses or less than 0.0001%). These include a serious allergic reaction, a prolonged seizure, a decrease in consciousness, lasting brain disease, or even death.
Major epidemiological studies looking at neurologic risks related to immunization have been unable to demonstrate a causal relationship between DPT and any severe, chronic neurologic disorder.
Many of the reactions to the older DPT (or DTP) injection were from the pertussis component. Children in the United States now receive the newer DTaP vaccine rather than the older DPT vaccine. The DTaP vaccine is a newer and safer vaccine because the pertussis component has been changed.
My seven year old son has never been dry at night. My friend says he must have some emotional problem and I should take him to counseling. His father wet the bed until he was 9 or 10 years old. Could there be a genetic link? Should I take my son to counseling or is there other treatment? It's becoming a real problem for the entire family and I don't know what to do.
Fresno, California
Contrary to popular opinion, bed-wetting is a very common problem. It affects somewhere between five and six million children. Unfortunately, most of those kids and their parents feel that something must be emotionally wrong; that they must be suffering from low self-esteem, trauma, or stress in their lives. The great news is that, in the vast majority of cases, this is not true!
Bed-wetting, or nocturnal enuresis, can be divided into two types: primary nocturnal enuresis and secondary nocturnal enuresis. These two types are very different in their causes and treatments.
In primary nocturnal enuresis, children have never achieved complete nighttime control - always wetting at least two times a month. Secondary nocturnal enuretics are completely dry at night for a period of at least six months and then begin wetting again.
In secondary enuresis, the key is finding out exactly what has changed. There might be a new psychological stress such as a divorce, a move, or a death in the family. It might be something physical: the onset of a urinary tract infection or diabetes, for example. It might be a situational change - perhaps altered eating, drinking, or sleeping habits. Clearly, something has changed. The first step in solving the problem is identifying that something.
The great majority of bed-wetting children are primary enuretics. For primary enuretics, the cause is decidedly NOT stress or behavioral concerns. Research has shown that primary nocturnal enuresis is often inherited. If both parents were bed-wetters, 77% of their children will be. If only one parent was, 44% of their offspring will be. If neither parent wet the bed, only about 15% of their children will wet the bed. With primary nocturnal enuresis one almost always finds another relative who was a bed wetter. This corresponds to what is called an autosomal dominant inheritance pattern.
In recent years, researchers have identified an association with bedwetting and two genes named ENUR1 and ENUR2. The ENUR1 gene is located on the 13th chromosome while ENUR2 is found on chromosome 12. In studying certain families with primary nocturnal enuresis, researchers discovered that members who wet the bed were more likely to have the ENUR1 or ENUR2 gene than those who did not. More recently, the possibility of a third primary nocturnal enuresis-related gene (ENUR3) on chromosome 22 has also been uncovered. Presumably these genes affect either whether children will need to urinate at night or how easily they can wake up when their bladders are full.
If your child has primary nocturnal enuresis, I would not take the child to counseling to solve the problem. It is quite likely that if nothing were done, your child would wet the bed until about the same age as his father. There is no reason to wait until age nine, since effective and safe therapies are now available. The best way to pursue help is to talk with your pediatrician. If you find that for some reason she or he is not able to get your child dry quickly and effectively, I would call the closest Children's Hospital to find out who treats bed-wetting issues.
Whenever a parent and a young child have to be separated for an extended period, it is difficult for both parent and child. Click here for tips on helping young children deal with temporary separations.
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