Are they really my parents?

If both of my parents have O positive blood, is it possible for me to have O negative blood? I have been told that it is not possible, that one parent would have to have the negative factor. I have been researching this question for some time with no good answer. I would really appreciate your help in answering this.
Debbie Howlett – Farmington, New Mexico

Are they really my parents?

Dr. Greene’s Answer:

Genetics can be so confusing! I can easily see how after much research the issue would still appear murky.

The modern science of genetics had its start in 1866 when an Austrian monk named Gregor Mendel provided a simple yet powerful description of how traits are passed on from one generation to another. Mendel’s work was unappreciated until 1900 — more than fifteen years after his death. In his initial formulation, he described how sexual beings get two genes for each trait, one from each parent. The trait expressed, or visible, is a result of the interplay between these two genes. Specifically, he recognized that some genes are dominant and some are recessive. If you have one copy of a dominant gene you will express that trait, regardless of the other gene. In order to express a recessive trait you must have two recessive genes.

Mendel’s first experiments, though simple, were quite profound. He worked with peas, which had easily distinguishable traits, such as green versus yellow seeds. Each pea has two seed-color genes, one from each parent. The peas with two yellow genes were yellow. Those with a yellow and a green gene were also yellow; only those with two green genes turned out to be to green. Thus yellow was dominant over the recessive green gene.

The situation with human blood genetics is far more complex, since at each point there are multiple possible characteristics. Nevertheless, the genetics of human blood is far better understood than that of any other human tissue. While there are rare exceptions, the following information on blood types applies to most people.

First, let’s look at the ABO blood types. Each person receives an A, B, or O gene from each parent. In this system, the A and B genes are co-dominant and the O gene is recessive. Thus, a person whose genetic type is either AA or AO will have blood type A, those with genetic type BB or BO will have blood type B, and only those genetic type OO will have blood type O. This means that a child with type O blood could have parents with type A, type B, or type O blood (but not with type AB). Conversely, if two parents both have type O blood, all their children will have type O blood.

Another medically important blood type is described in the Rh system. These genes were first discovered in the rhesus monkey, hence the designation Rh. The Rh system is actually far more complex than the ABO system in that there are 35 different possibilities that one could inherit from each parent. These, however, are roughly grouped into positive and negative types. In this system the positive are dominant over the negative. If your genetic type is ++ or +-, your blood type will be Rh positive. Only if your genetic type is — will you be Rh negative. This means that if both parents have Rh+ blood with the +- genes, they could have children who are ++, +-, or –. In other words, their children could be either Rh positive or Rh negative. Children who are Rh negative can have parents who are either Rh positive or Rh negative.

Two parents who have O positive blood could easily have a child who is O negative. In fact, most children who are O negative have parents who are positive, since the +- combination is so much more common than the — combination.

As it turns out, there are more than a dozen complete blood group systems other than the ABO system and the Rh system. This makes great precision possible in looking at inheritance and family trees.

There is no reason, based on your blood type, to suspect that your parents might not really be your parents. If questions linger for other reasons, specific tests are available through blood banks and private laboratories that can settle the issue. These tests are commonly known as paternity and maternity DNA testing (for father and mother respectively). Given the billions of unique people on this planet, the power and precision of genetic testing are amazing.

Dr. Alan Greene

Dr. Greene is the founder of DrGreene.com (cited by the AMA as “the pioneer physician Web site”), a practicing pediatrician, father of four, & author of Raising Baby Green & Feeding Baby Green. He appears frequently in the media including such venues as the The New York Times, the TODAY Show, Good Morning America, & the Dr. Oz Show.

  1. Cate

    I’m one of 8 children born to the same parents. Both parents are O+. I’m the only child out of the 8 with O- blood group. I have 4 children to my ex husband who is O+ and 2 of them are O+, 2 are O-.

    It seems very odd to me that out of 8 I’m the only one but out of 4 we got 50/50!

    I also have some illnesses that are inherited and I’ve passed to one of my granddaughters. Is it possible my father isn’t my father?

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    • Odds are a strange thing. With two O+ parents each child has a 6.35% chance of having O- blood. That means out of 10,000 children born to two O+ parents 625 of them should have O- blood. But each child is either + or -. It’s like rolling dice. You should get a 6 once out of every six rolls, and yet you don’t. You may get three in a row and not get another the next 100 times you roll. If you roll long enough (unless the dice are loaded) it will average out to 1 in 6 rolls.

      Does that make sense?

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  2. Mishal

    my parent’s blood group is o+ve but mine is B+ve is there any chance for this type?

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    • Two O+ parents can only have children who are O+ or O-. However, as Dr. Greene points out in his Q&A Blood Types 102, “These are general rules, though, and exceptions apply. Very rarely, gene mutations may change the rules such that “impossible children” become possible.”

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  3. Candace brooks

    Hello…
    I just had a baby she is B negative and I am O positive I was just wondering what blood type would her father have to have? Really freaking out. Can you inherit blood type from down the line?

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    • In this scenario, the father would be B+ or AB+. For a full explanation go to Dr. Greene’s Q&A, Blood Types 102.

      Hope that helps!

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    • Candace Brooks

      Hi, me again. Is there possible that babies can inherit a blood type from down the line?

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      • I don’t know what you mean “from down the line”. Do you mean from a previous generation? Such as a grandparent?

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        • Candace Brooks

          Yes.

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          • We all are impacted by our ancestors. In blood types, we get one gene from our father and one from our mother. It is possible in that way for a gene to pass “silently” from a grandparent to a parent, to a grandchild — but that is accounted for in the information I’ve already provided.

            Please keep in mind, as Dr. Greene points out in his Q&A Blood Types 102, “These are general rules, though, and exceptions apply. Very rarely, gene mutations may change the rules such that “impossible children” become possible.”

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  4. Lindsay

    I am one of three children born to the same parents and I am the only one with O- blood group, I found my blood group out when I booked in for my first pregnancy and at the time my Doctor raised her eyebrows but did not pursue it, anyhow I have reason to believe that I am not the biological daughter of my Father and my Parents blood types are as follows:

    Mother O+
    Father O+

    Child 1 O+
    Child 2 O+

    Child 3 ( me ) O-

    My Grandfather is the only person in our Family apart from me who has a negative blood group and he is A-

    As I understand it is possible that he passed on a O+- to my Father, but then wouldn’t my Father have A+- blood grouping as I thought that A was always dominant over O? I am confused by the possible permutations to this issue as it could potentially cause a huge split in our Family with my Father questioning his own paternity as well as trying to resolve my Paternity,

    I have ordered a DNA testing kit which my Father and I will both take so we can finally put this issue to rest but any advice reference my Grandfather not being my Fathers biological child would be very appreciated.

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    • There is a 6.25% chance that every child of two O+ parents will be O-.

      As to your question about your Grandfather’s blood type and what he might have passed to your father — do you know your Grandmother’s blood type? Without that information it’s just speculation.

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  5. Anonymous

    DR. Greene her question was can two O+ parents give birth to an O- Baby? You threw a lot of info out there except for the answer. If your parents are both phenotype O+ O+ then their is no way that they could have an O- Baby..But if they are O+ O- hybrids than yes they could just like an AO or BO can have an OO if they marry one because they two are hybrids If an O- O- marries an O+ O+ yes the baby will be O+ O- but if that son or daughter marries an O+ O+ it could be O+ O- but most likely it would be O+ O+. Likewise if an AA+ person marries a OO+ person the children will be AO+ and if an AO+ person marries an OO+ person the child could be OO+ or AO+. That’s how genes work if the AO+ dads O+ sperm happens to attach itself to the moms O+ egg than the baby will be OO+ or if the A+ sperm attaches itself to the O+ egg the baby will be AO+. If the parents are both AO they could have O or O babies and it works the same way with BB OO BO babies as well. AB is extremely rare blood 3.4% of the worlds population have it and 0.6% have AB- all totaling 4% of the worlds population. O is the most and A is a very close second and B blood is kind of rare as well. I hope this helps. I want to note that AO BO and O+ O- A+ A- B+ B- are hybrids where one acts as a silent business partner but yet can be inherited and fully activated. There is no excuse for we have been aware of this for a long time.

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  6. Michelle young

    I am A neg…is my blood rare? Should I donate my blood regularly?

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    • According to the American Red Cross:

      O+ is the most common blood type. Not all ethnic groups have the same mix of these blood types. Hispanic people, for example, have a relatively high number of O’s, while Asian people have a relatively high number of B’s. The mix of the different blood types in the U.S. population is:

       
      Caucasians
      African American
      Hispanic
      Asian
      O +
      37%
      47%
      53%
      39%
      O –
      8%
      4%
      4%
      1%
      A +
      33%
      24%
      29%
      27%
      A –
      7%
      2%
      2%
      0.5%
      B +
      9%
      18%
      9%
      25%
      B –
      2%
      1%
      1%
      0.4%
      AB +
      3%
      4%
      2%
      7%
      AB –
      1%
      0.3%
      0.2%
      0.1%

      The people with O- blood are universal donors. Only 9 percent of people in the U.S. have O-negative blood type. O-negative blood type donors are universal donors as their blood can be given to people of all blood types. Type O-negative blood is needed in emergencies before the patient’s blood type is known and with newborns who need blood.

      People with A- blood are not universal donors, but if you are a healthy person, donating blood is a great way to help others.

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  7. Michelle

    If I am O rh negative and my husband is B positive. What are the possibilities of blood types of our children?

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    • Hi Michelle,

      There is a 75% chance each of your children will have B blood type and 25% chance of O. There is also a 75% chance each of your children will have Rh+ blood and a 25% chance of Rh-. So the possible combinations are:

        O+
        O-
        B+
        B-

      Hope that helps.

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  8. Alison

    I (mother) have O- blood and my daughter has B- blood. Can her dad be a B+ blood type?

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    • In this scenario, the father could be B- or AB-. If you have questions, it’s always smart to retest before jumping to any conclusions.

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    • Candace Brooks

      Same question here.

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  9. Linda

    When I was pregnant with my son, I found out my blood type, which is A+. I had told my mom. She kind of freaked and said that’s wrong — dad and I have O. I am totally confused. My dad since has passed. His dog tags say he has O, I’m not sure if neg or pos. Can you help me try to figure this out? Thank you.

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    • Two O blood type parents can’t have a child with A blood type. It’s not uncommon for one of the three blood types to be reported incorrectly, however.

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  10. Holly

    My mother is a+ and my father is b+ but I’m o-! There is question if my father is truly my blood father. I was just wondering if that is possible.

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  11. Nadia

    My mother’s whole family (grandparents, parents and siblings) are all A+ and my dad’s whole family are all O- (grandparents, parents and siblings). My sister and brother are both A+ but I am O+. Am I right in saying that it can’t be correct?

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  12. Gabywd

    I just found out in my 3 rd pregnancy that I am B – , my husband is O + and both my parents are B + . My first two daughters are B + and at the time I thought I was B+ and I didn’t have any “shots” is this possible? I have been tested 3 times and they all come back B negative very confused !

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  13. Sarah

    Hello my blood type is O- and my both parents is O+ is that possible???!

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    • It is uncommon, but possible. In fact there isa 6.25% chance that two parents with O+ blood will have a child with O- blood.

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  14. jallusion

    Hi my family all their blood type s are o++ or o+- and I’m the 4 child but I’m the only 1 with b– what’s wrong with that’s?

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    • This is possible. For instance, if one parent had A- and the other had B+, they could have have children with either – or + Rh and could have children that are A, B, AB, or O.

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  15. Elena

    hello,
    I have A+ and my husband has B+, our deceased child was AB-.
    Could this be possible?
    they didn’t find a diagnostic, could be something linked to her blood type?
    thank you so much

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    • I’m so sorry for your loss.

      It is possible for an A+ parent and a B+ parent to have a child with AB- blood. I can not tell you if it had any impact on your child’s health. Perhaps you could visit a geneticist for more information.

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  16. olue

    I am o+ so also my wife but our first daughter was o-. can it be possible? Though we are all AA genotype.

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  17. Hemant

    is it possible that fathers blood g is AB- , mothers blood g B- …than daughters will be A-….

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  18. Beki

    Hi I am O- blood type and my daughter is AB- her fathers blood type is unknown, what could his be?
    Because I’ve read that it’s not possible for an O- female to have an AB- baby?

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  19. Brittany

    I am O+ my daughter is AB- tested at birth due to some complications and I know for a fact that I’m O+ because I received blood… Not the doctor was confused and scratching his head when talking to me about it but… O+ can have AB-

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  20. Regina

    Hi, my mother is A+, my sisters are A+ and A-, I am O. Is there anyway to decipher what my father’s blood type is?

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    • smarty p

      is that a homework assignment?

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      • Jane

        He also could have been A or B or O.

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  21. KB

    O+ mother, A- father. O- negative. Could that be? How is the RH factor determined? I was tested by a blood center because I donate, I was told my childs type by a nurse @ her pediatricians office and the father thinks that’s what his is. Just wanting to double check that a child could be O- if the mother is O+. —-Thank you.

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    • A mother with O+ blood and a father with A- blood have a 75% chance of having a child with type A blood and a 25% chance of having type O blood.

      A mother with O+ blood and a father with A- blood have a 75% chance of having a child with Rh+ blood and a 25% chance of Rh- blood.

      For a full explanation, see Dr. Greene’s article Blood Types 101: An Introduction to ABO Blood Types and the Rh System.

      Hope that helps!

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  22. Carolyn

    I’m an AB- and I just found out my father is O+ can this be possible? I always thought if I was AB- that my parents would have Co-dominant alleles AA, BB, or AB for me to result in AB. SO you can imagine my surprise when I heard that my father is O+ How can this be possible? Unless…

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    • That combination is not possible, but blood tests are sometimes wrong as are memories of test results. It’s wise to double check, before making assumptions.

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  23. Fathimakm

    Sir my mom blood group is A1+ and my father blood group is B+ and my blood group is A1B+. Is this blood group is considered in type of blood group many are telling this blood group is not considered now and weather. Is A1B+ considered?

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  24. abhaille

    We have three children. I’m O+ and we don’t know what my husband is. Two children are O- and one is O+.

    I’m thinking he’s O-. What are the odds?

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  25. Anonymous

    sir…i am having AB positive bloodgroup and my wife B positive bloodgroup and my child O positive ..is this possible

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  26. Alex

    My parents has type O as their blood type. And when I was diagnose with dengue the doctor said that my blood type is AB. Is it possible for me to have that blood type even though my parents are both type O?

    Hoping for your response. Thanks.

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  27. Nikita

    My blood group is O+ and my Husband is B+ now our child blood group is AB+. Is it possible?

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    • Children of an O+ parent and a B+ parent have a 85% chance of being blood group B and a 25% chance of being blood group O. Each child of those two parents have a 93.75% chance of being Rh+.

      Perhaps it’s time to have both parents and the child re-tested. Or consider that one of the parents is not the biological parent.

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  28. Backatchatwice

    I have a question, not a comment.
    What are the odds of A+ and B+ parents having a B- child?
    Would the A+ mother reject the B- child at some point;
    like with an Rh negative mother and a Rh positive fetus?

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  29. mary

    Both my parents are deceased. Is it possible to obtain their blood type results from a source somewhere? Mine is rh positive with little c antibodies since the birth of my first child. I would greatly appreciate some help.

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  30. Jenni

    I recently found out I was blood group A, but my parents both are pretty sure they are both O. If this is correct does this mean they are not my parents?

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  31. Peter Ngu (Wu)

    I do not know my deceased parents blood types. All my brothers and sisters (7 of them) have Type A Blood type. I am the youngest and have Type O blood type. The one above me is my sister who is 8 years older than me. Is this type of non similarities possible. Hope to hear from you soon. Thank you

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    • If one parent has type O blood and the other is type A, 75% of their children would have type A blood and 25% would have type O blood. What that means is each child has a 75% chance of having type A blood and a 25% chance of having type O blood. Theoretically, that means 2 out of 8 children would be type A, but in reality, each child could be either type A or type O.

      For a detailed explanation — Blood Types 102: The Role of A, B, O, and AB Groups In Determining Paternity.

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  32. EMMA

    I am O+ while my mum is O-. What blood type/group will my father be. This question has been killing me as my mum have no idea and I discovered my dad is type A, could he be my dad? Really urgent.
    Thanks

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      • savannah Ray

        My mother and father are both O- and I’m O+. Is that possible?

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        • If both parents are O-, their children will be O-. But often one of the three parties either don’t remember their test results correctly, or the tests were wrong. Testing errors do happen. Before jumping to conclusions, you should all re-test. If this is a serious concern, paternity testing is the most accurate way to determine who your father is.

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  33. Annemarie

    if I am O positive and my mother is O positive and my father is AB negative RH does this mean he is a match or not please get back to me asap would appreicaite it thanks x

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  34. Chanel

    my sister and I have grown up being told we have different dads. We have the same mum. Yet I never met my father. We recently gave blood and found out we are both B- blood. Does this mean we do have the same father? Our parents have passed so we can’t ask them.

    Many many thanks

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  35. Cleasy

    My wife has O neg blood type and I am AB pos but our son is B neg. I thought AB would have been the dominant type.

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  36. nessie

    Hi there, both my parents are A+ve and I am A-ve ? According to my family, no one is negative? Can that be? My sister is A+ve.

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  37. Evelyn Bakic

    I am O+ i have 3 daughters my eldest is O+, second is A+, and the baby is not typed yet. What would be my husbands blood type? He is not a fan of needles so getting him tested just for typing is out of the question.

    Thanks

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    • anonymous

      Since you are O type and have an O type child and an A type child, this means the other half has to be A type. As per + or – could be either. Your third child can be either an A or O + or -.

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  38. Clare

    I’m O Rh Negative and we found out my daughter is O positive due to her needing tests when she was very small.

    We also have a little boy who we don’t know his blood group and my husband doesn’t know his – any ideas as to if my son would also be an O positive and would my husband also be O?

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  39. karysma

    My moms B- and I’m Ab+ and my dad doesn’t really know his blood type. She said he was either B or O. But then I told him I couldn’t be his daughter if he was so I asked him again. Now he is saying he is A+. What should I do?

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    • You could have your answer with a simple blood test from your dad. You could say something like, “Dad, I’d like to know the blood types of both you and mom. This could come in handy for health purposes down the road and it would put my mind at ease about our relationship. Is that something you can do for me?”

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  40. sabina

    I’m O positive and my husband is O negative. Are there chances my child will have rh negative?

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  41. kerry till

    I’m a rhesus b negative and my sister is ab positive,is it possible we could be full sisters?

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  42. Febi Francis

    both my parents are o+ and I’m AB- is this possible

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  43. Diana

    I have a+ blood an my mother is o+ an my father is b+.. I don’t think they are my parent what do I do?

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    • You are correct that those combinations can not occur. The first step is to discuss your fears with your parents. They may say they are indeed your biological parents, and one of the blood types is incorrect. It’s pretty easy to have all three of you re-tested. Or this may open the door to a conversation about your adoption.

      If you think there is a possibility that your mother is your biological mother, but your father isn’t your biological father, you may want to talk with her alone before including your father in the conversation.

      Unless you have reason to think your parents are hiding something from you, this should be a calm conversation that simply explains your heritage more fully.

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  44. Sharon

    Please help. Desperate!
    My Parents both have RH- blood types.
    I am RH+
    How?
    I was born with severe Anemia. .mother needed Rogram shots after me.
    My Uncle is RH+ !!!!
    Please tell me if my parents couldve produced me..or did the someone mess up!!
    Im 54 I dont mind anymore.

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  45. dt

    I was watching a TV programme where the dad was ab and mum o and the baby was o, so it was concluded that the dad was not at all the dad!

    My eldest sister is type o and our mum is o but dad ab rh negative. I am A rh negative as is my other sister. Could our dad be my eldest sisters dad? She is o positive like mum, but we are all A negative and dad is AB negative! She’s the first born, is she my dad’s? From the info on here she can’t be?

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  46. Yvonne Shepherd

    I have been diagnosed with chronic kidney disease. It does not run in my dad’s side of the family and I have never met my birth mother So I’m assuming I inherited it from her side. I’m trying to figure out what blood type my birth Mom would be. My Dad is O+ and I am A- rh- factor . Could anyone please help?

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  47. Jan

    Hi my parents are both O+ I am A- is this possible

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    • Tina

      No I would be asking your parents some questions sorry but it not possible for to 2 Os to have an A

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  48. Mark Trevellick

    Can a b poss father and a o poss mother have a o neg baby

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    • Tina

      Yes

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  49. Freida

    I have a question, my Dad is O+, but my Mom is A+! My question is, is she my mother?

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    • Freida

      Sorry just read my question, I am O+ my mother is A+ can she be my mother? My dad was O+!

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      • Andy

        Yes, if your parents are A and 0, the child can either be 0 or A.

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  50. figo

    I was tested B+ blood group and my wife to be is 0+ blood group. And in my country, Nigeria, there is this genotype blood that is not familiar to other doctors outside the country and that is AA, AS, SS blood genotype. Universally where does this blood genotypes falls into? Please I will be happy to see my questions answered.

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  51. Carla

    If both parents have A positive blood, can they have a O negative child ?

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    • The short answer is yes.

      If two parents both have AO +- genes, they will both have A positive blood and about 1/4 of their kids would be type O and about 1/4 of their kids would be Rh negative, so about one out of sixteen times they would have an O negative child.

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  52. shefali

    hi…..i belong to india,rajasthan

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  53. Rohit

    Well b+ is a blood group for a CHILD. Now A+ is mother and O+ is father.
    What is the chance of getting a B+ CHILD??

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    • Evan

      I don’t think it is possible. According to my Introductory Bioscience lecturer the only way a child can be a member of the B blood group is if one of the parents provides the B to the genotype. In simple terms a member of the A blood group can only be AA or AO while a member of the O blood group can only have oo. As neither parent has the B antigen markers in their blood no offspring of this relationship can be blood group B.

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  54. Afna

    i’m Afna…My question…..Parents having AB+(Father,Mother)….but children having(1st:AB+,2nd:A+,3ard:AB+).please explain its chances….?

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  55. shefali

    my sister has blood grp ab+ and both of my parents hav o + is this possible. She is first child of my parents

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    • Tanvir

      Shefali, can i know where you are from? I am trying to research on this matter…I wont give the verdict, but the cross typing doesn’t really show the possibility of making AB+ out of two O+ parents…But again its all GENETICS…and needs more research! Are you from Bangladesh/India or any of SEA?

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  56. Catherine

    My parents are both O+ but in a recent test my blood seemed to be B+ is that possible?

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    • Tanvir

      Are you first child?

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      • Rohit

        Dear Tanvir,
        Yes I am the first child of my parents .
        Or no???
        Tell me my Blood Group is B+ and Fathers group is O+ my mother is A+.
        Now are they my real parents?? or Tapake Khazuur pe ?

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    • maddy

      both of my parents are b + n I m o+ but younger sis is b+.., in science, everything is possible so chill

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  57. pamy

    I am from India, I m a man of O negative blood. Can I marry to O positive women? What will happen to my baby? Can I marry to A blood group? What will happen to my baby? Can I marry to B blood group women? What will happen to my baby? And my last questions is I heard that all the guys who have A negative blood have less genes which lead to no children in life? Is that true?

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    • abhaille

      You should have no problem marrying any woman that would have you. O negative is the universal donor. Women are the ones that have the trouble having negative blood type when having children.

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  58. Carol

    Can a person have blood group O and neither parent have that blood group?

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  59. I. McNutt

    I was born to a mother with AB- and a father as O+. I was the second child and mom never had any shots after her first birth or when carrying me. Can this cause health issues for the second child? And if so what can the issues be? I have had a lot of health issues my entire life one thing after another could this be why?

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      • Diana Harris

        I can truly relate to I. McNutt in that I’m also the 2nd baby of Rh incompatible parents (my mother being untreated since it was the 1950’s). However, in my case my elder sister was actually the blue baby, born in ’54 she died after just a couple of days.

        I always thought of myself as a miracle baby since I should’ve been the one to suffer that fate being 2nd, yet was born healthy in ’56. When my mother was almost 40 (this essentially was her last chance to have her long desired baby girl).

        I’ve often wondered how I was unscathed, perhaps you can answer this? Anyhow like I. McNutt I’ve suffered a myriad of chronic health ailments even as an adult – between the age of 25-30 is when they presented (psoriasis, psoriatic arthritis, fibromyalgia, chronic fatigue, fibrocystic breasts, hypothyroidism, osteopenia which now is osteoporosis, neuropathy) & have wondered as well if this was connected to the Rh factor situation. I’ve felt like I’m in my 80’s since I was 30 being crippled up in pain, constantly at doctors & labs, medications etc.

        As a child I nearly died from complications of bronchitis when I was 2, had recurrent bouts of hives (even into adulthood) & the usual childhood illnesses (measles, mumps, chicken pox). I’ve been severely nearsighted since I was 7 (Coke bottle glasses) which now has put me at high risk for some type of retinal detachment & bleeding so must be monitored at least every 6 mos. I’m 58, but the last 30 years (when I was still relatively young) have really drained me & I’ve a hard time envisioning another 30 years of pain & struggle.

        I can’t help thinking if my health conditions stem from the Rh issue then something could be done that would target the source & I finally could get better. I recently was diagnosed with major depressive disorder & that has to do with all of this & how life is getting harder for me – just to do the basics. On the Yahoo Q & A another Rh person had written similarly how they’ve suffered with their health & their siblings had all died by their 40’s.

        Have there been any studies done of babies (born prior to 1963) of Rh incompatible parents & their health outcomes as they mature? Are those of us writing in who are sick merely flukes? is the Rh incompatibility & illness just coincidental or is there a pattern & one worth investigating? I welcome & would be most grateful for any information & opinions you could provide.

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  60. John J

    If both parents are O+ , and they have three kids that are O+. Is it possible for a fourth child to be O-?

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  61. stumped

    I have 2 children with o+ blood type, I am o+ and my husband is o+, he has a daughter from another woman and this daughter has ab- blood type, the daughter says her mothers blood type was also ab-. Is is possible that this is his daughter?

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  62. payal

    My brother blood group is “O”positive and my sister in law blood group is “AB” negative but my nephew blood group is “B” positive it is possible or not?? Plz help us..

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    • It’s not the most common blood type from this mother and father, but this is possible.

      Each person receives an A, B, or O gene from each parent. In this system, the A and B genes are co-dominant and the O gene is recessive. In other words, both parents must have type O blood for their children to have type O blood.

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  63. Rose

    My parents were blood o group but my brother is a resus negative mine is a possitive can this be ??

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    • From the information you’ve given, it’s impossible to know for sure. If both your parents were O- all their children would be negative, but if either of them were O+, this is a possible combination.

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  64. christy

    Yes my blood type is ab+ and one of my daughters just found out her blood type is b- Her father is adopted and he doesn’t know his blood type. There is a chance he could not be the real father, so what would his blood type have to be to be compatible for him to be the real father? Please help!!!

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    • Your daughter’s father would have blood type A+, B+, AB+, or O+.

      Hope that helps.

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  65. Edward Hines

    My mom is O+ and dad is B+, how can I be A+, help please?

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    • Linda

      Hello Edward,
      Did your question ever get answered?
      I have the same situation and further digging has pulled up some anomalies that could make this true…

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  66. Glen

    My parents and brothers and sisters are all O type not sure about pos/neg. Why am I AB positive? Is there something my parents should tell me?

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    • C

      Maybe there’s something at least one of your parents should be telling you. And your dad. :)

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      • Before jumping to conclusions, you may want to consider a few key questions:

        • Was I wanted?
        • Do my parents love me?
        • Will it hurt my father if I open this can of worms?

        You may have been a much desired child that your parents were able to conceive with the help of a sperm donor.

        Or one of the three tests may be wrong.

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  67. sabillah

    My parents both are o+ and mine is B+. Is that possible? I’ve been wondering.

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    • Two O+ parents can’t have a B+ child, but consider:
      — Perhaps all the tests aren’t correct. Test errors do happen.
      — Perhaps someone’s memory of his or her test results are wrong.
      — Even “impossible” results happen. They are very rare, but genetic mutation is real.

      If this is of concern, consider DNA testing to determine paternity.

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  68. nav

    sir…i am having AB positive bloodgroup and my wife B positive bloodgroup and my child O positive ..is this possible??

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  69. Chris

    I saw a case where both parents are O+ but all their children are A+. How can i reconcile these?

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    • Pat

      Both my mom and dad are gone, both of them are 0 positive, including my brother , but I am A Positive

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  70. marwan john

    am b negative and my wife o negative it is posssible we have a positive child ???

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  71. Shirley

    Father A negative Mother O Negative child A positive. Is it possible this man to be the dad?

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    • Ashleigh

      YES… II just had my son 2 days ago… I am A- and his father is O+… Our son is A+… A type is dominate over O type and when you have a – + combo the + is dominate… So you would end up with an A+ Baby…

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  72. Courtney

    My mother is ab negative and my father is o negative. I’m o negative. How is this possible if an ab blood type can’t parent a o blood type?

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    • Michelle

      I am almost 100% sure that my husband tested AB-. I was pregnant and found out to be negative, so we tested my husband. I am O-, both my children are O- as well. The only reason I say almost 100% sure dad is Ab, is because after reading this article I began to question my memory..lol..I cannot find the labs report to check for sure. But after this article, I’m extremely curious to find out for sure. Just sharing.

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  73. Mainlay Jasn

    Suresh Mathur … My mother is O+. My dad is O+, but I’m O-. My little brother is O+.
    So, you’re wrong.

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    • Alexis Brown

      He is not wrong however, you are mistaken. Each person has 2 RH factors either ++, +- or –. He explained all variables in his examples.

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      • Courtney

        Mainlay was speaking to someone who commented and was wrong. Js.

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  74. Suresh Mathur

    Hi,
    Me and my wife both blood group is O+, and my new born baby boy also O positive.
    I think that if parent are O+, all baby will O+.
    Thanks Doc For nice article.

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  75. Liana Hernandez

    Hi my blood type is A + and my husbands is A- so when our child was born she was an O + . We took a DNA test to confirm which proved this can happen.

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  76. patty balser

    If I have RHO negative blood, what would my parents blood have to be?

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  77. subir dutta

    my blood groupe is A ..and my wife is B …but my son’s groupe is O ..is it possible

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    • Alka Gupta

      Yes.. It it is possible coz u have A group means u r carrying A nd O gene nd ur wife have B group means she is carrying B and O gene…so ur baby can take one O from u nd another O from ur wife nd ur baby’s blood group vil be O

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    • davidpaulabraham

      My wife and i are 0+ what is my baby blood group???

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    • Srinivas

      Mother A positive,Father B positive.child O negative.Is it possible

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  78. mich

    Hallo

    Can a baby’s blood be B+ if the mother is A- and the father is type O (not sure if – or +)?

    Please help.

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    • Harsha

      I just saw your query…..i am not good at biology it cannot be possible to have B+ if parents are A- and o(+ or -)….you just refer to this link http://www.endmemo.com/medical/bloodtype.php ….. the result i got is NO

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    • Alka Gupta

      No it is not possible… One of the two parents must have B gene … Otherwise it is not possible.

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  79. tyshauna joiner

    Can o positive people have a healthy baby?

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    • anita k

      We are both o+. Won’t our baby have difficulties in health?

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  80. Rajesh p

    Docter I am simply verifing my blood group is O positive and wife blood group is B positive but my baby is b positive it is possible sir

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  81. yash

    THANK YOU SIR I HAVE FOUND THE ANSWER FOR MY QUESTION IN THE ARTICLE BLOOD TYPES 102

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  82. yash

    Sir,I have a question my cousin’s parents are B+ and my elder cousin brother has B+ but the case of his younger brother he has O+ IS THIS POSSIBLE ? Please reply to this on my mail address.
    THANK YOU

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  83. chantelle

    As I understand I was a “blue baby” during birth and needed an emergency blood transfusion.

    My Mother is A+
    My Father is A+
    But I am AB+ (this is impossible because two A… cant produce an AB)

    Can this be caused due to the blood transfusion that I receaved after my mother gave birth to me?

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  84. Aaron Forrest

    Hi my mother is o negative. I don’t know what my fathers blood type is, but mine is ab positive. Research I have done on the internet says this is impossible. Can some one please explain?

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    • Courtney

      Your father might have ab blood. it does say an ab can’t parent an o

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  85. Kyle

    Both the wife and I have O+ blood. How can we have a baby with A-? I understand that we both are (+,-) so we can have a child that is O- but how is it that the baby is A? The doctor told us that this is very rare. I just want to understand how.

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    • Becky

      I am very interested in any answers you find on this subject, Kyle.

      I am very obviously not adopted, but just recently I found out that both my parents are type O (dad is O+), two out of three siblings are O+ (one sister doesn’t know her type), and all three of my children are O+. I am type B (I don’t know whether its positive or negative). To my knowledge I’ve never had a blood transfusion. Everything I’ve searched online states that this is not possible.

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      • Fiona

        I’m very interested in what you have found out as well. Both of my parents are O+ and I am B+. I’m just very confused as from my very basic Biology it’s not possible?

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    • Sabrina

      Same has happened to me and my husband. He is o- and I am o+ but our daughter was born A+. I hear about this happening in many other cases.

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  86. Jules

    Hi my mom is an o+ and my father is a b- and I found out during the labs for my pregnancy that I’m an a+. That isn’t possible is it?? I have other reasons to be suspicious but does medically prove that it is impossible for them to both be my biological parents?

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  87. Anushree

    So my mom’s blood group is B-ve while my dad’s is B+ve, but I’m AB+ve. They say that in rare cases it is possible for the blood group not to match, but I’m still skeptical about it. Can you help?

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  88. Katie webb

    My blood type is b-and my twins are o-my ex husband doesnt think he is the father but his blood type is o- as well could that mean he is the dad

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    • Tish

      I’m O- and my son is O-, my husband is O+, there is no question he is from us both as he was born by in vitro fertilization.

      Ha ha — unless he was ‘switched’ at birth, but highly unlikely-he looks like both of us no doubt.

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  89. "M"

    My mom is A+ , my sister is O- and I am B-. Is this possible and so we have the same dad?

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  90. love

    What about pregnancy if my blood group is b- and my wife o+?

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  91. Rajesh p mysore

    Docter sir I’m confused. My blood group is O positive and my wife’s blood group is B positive and my son blood group is B positive. Is it possible?

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    • Henk

      Yes, this is possible.
      The gene types of blood group B are BB and BO. The gene types of blood group O is OO. Your child must have gene type BO (the B inherited from your wife and the O inherited from you) making him having blood group B.

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  92. sai

    If you have parents with same O+ blood, would it be possible if they bear an A+ offspring? Please answer because I really want to know if I am really their daughter.

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  93. Larry Richardson

    Hi Dr. Greene.

    Both of my parents are deceased. When my mother was alive, she told me she had the rarest form of blood: AB negative. My father’s dog tags, from the military, indicate that he was O positive.

    From photographs and time sequences for conception, there are doubts that the man I called father is really my blood father. The disparities in physical characteristics, the manner in which we were treated growing up, and our psychological makeup are extremely distinct. My brother was the first born, and has blood type O negative. I am O positive.

    I am now 71 years old and only wish to verify if or not I was the love child of another second lieutenant while my father was in amphiibious training for the Normandy Invasion on D-Day.

    I have asked my brother if he talked about it with my mother since I left the house at 18 years of age and never returned until 20+ years later. He and my mother were best buddies and often palled around together. He says she never spoke of it. When I bring up the subject of how different we are in every aspect of our lives (physio, psychological, upbringing, etc.), he simply dismisses the subject with, “What does it matter?”

    Although I am an engineer, I have difficulty understanding the biology of blood types and Rh factors. Biology was not my forte in college!

    Thank you,

    Larry Richardson
    Los Lunas, NM

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    • Lucy

      Hi
      I am not an expert, but from what I have been reading about blood types, I think your mother was mistaken in saying she was AB negative…
      To have O children she would have to have an O in her genes, for example she would have to have been AO or BO.
      An AB mother would produce either an A or B baby I think…
      I could be wrong but this is my understanding.
      Maybe you could check this specific fact out.
      Lucy

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    • Sam

      Larry, perhaps I can hep put you mind at ease. I have the exact scenario in my family, and this is how a geneticist explained it to me. “This reminds me of a case in Japan. There an AB man and his O wife had an O child. Lots of research later, the researchers showed that he had his A and B genes stuck together on one chromosome and a “blank” spot on the other. What that means is that he could either pass AB to his kids or O and so with an O wife, he could only have O and AB kids.Another possibility is that dad has a really rare blood type called Bombay. These folks look O but genetically can be any blood type. If this were the case, then you and your brother might have the same blood type. Like I said, this is extremely rare.”

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  94. Rock

    My blood type is A negative my father is O rh positive what can my moms blood type can be and please what if both my parents have O positive are they really my parents please answer I am worry about:!?

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  95. Connie Jones

    Hi Doc: My brother and I are adopted and have been told that we are both from the same mother. Birth mother says, No, that she miscarried a boy before she had me out of wedlock… Long story..
    My question to you is..Can a sibling with A+ blood type and the other sibling with O- (Me)…be related?
    Just curious. Thank you..

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  96. Bridget

    i am confused …OK i have O- blood type and my Husband thinks his is A+(from blood test he did back in high school ).. we have 5 children all are O- so is that possible or is he really A-

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    • KIMBERLY ROBBINS

      I am trying to figure out the same thing during this pregnancy because I am trying to avoid getting a rhogam shot if my husband is positive, however, my husband is not sure whether he is positive or negative. I am O negative and my husband is A (something). All my kids (3 of them) are O negative as well.

      If your husband is positive, he could be ” ++ ” or “+ – ” which would still make him positive. If you are negative, then you are ” – – ” So, when you you do the calculations, your kids have the possibility of coming up “AO” which is simply “A”….OR….”OO” which is simply O. This is because you both pass on one letter to the child. For your kids to be O and your husband to be A, he HAS to be “AO”.

      As for the RH factor, he HAS to be “+ – ” so he can pass on a negative to the kids just like you. That would allow them to be O negative. So, yes, it is possible for him to be positive.

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      • Rajesh

        Docter I am simply verifing my blood group is O positive and wife blood group is B positive but my baby is b positive it is possible sir

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  97. san

    My blood group is O+. My wife’s blood group is B. My son’s blood group is AB. Is that possible?

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  98. sravanthi

    Both of my parents are B positive and I am B negative. This is possible?

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  99. Freda Arthand

    My daughter and I have the same blood type — O positive. Her dad (I think that’s he dad) has AB. We did a swab test and it was suppose to be her dad. However the guy I was with also had O positive blood. Could it be possible that the other guy is the father to my daughter? The one with ) Positive blood?

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  100. JC

    My sister is an O blood type. My mother is AB and my father is O. Is that even possible? Are they my parents or am i adopted?

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  101. patrick clancy

    if you have two parents one with o- blood and one with o+ positive blood is it possible to have two siblings with O negative blood and the other with o+positive

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    • Henk

      Yes, this is possible. Rhesus positive can have gene type ++ or +-. If one of your parents have +- and produce a child with a — gene type (Rhesus D negative; see explanation by Dr Greene), siblings can have both +- (Rhesus D positive) and/or — (Rhesus D negative).

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  102. Lisa

    Both my parents are O, my two siblings are O, but I am A. Is this possible?

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    • April

      No, two O make O

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  103. Ann

    What does it means if the baby have a A+blood type, and the mother is o and the father is o. A little confuse. Can you give me the answer
    Thank you

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    • Migdalia

      Doctor I don’t understand why my child came out with A+ blood type but me and my spouse have O+… Please help

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  104. mical

    Dear Dr….me and my wife are A positive …what shall my children blood group. ? I really like to know. .Thanks

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  105. Alexis

    I’m becoming concerned whether or not my parents are my biological parents. Everyone in my family has O++ blood and I’m O-, plus I don’t resemble any family members. I don’t know what to do?

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  106. Gyasi Dennis

    Both my parents have type O,but i have type B-,please is it normal?

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  107. Ashley Chambers

    Okay i need help understanding i am not sure of mine or my parents blood types i do know my sister is o begative with rh negative does this mean i too will be rh negative.? My next question is i have been cleared from a dr saying i have no fertility issues as has my husband but in 8 years were not parents yet is it possible that our blood types could be not compativ
    ble causeing us not to be able to get pregnant?

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  108. TheOtherRosie

    That sounds simple enough. Parents each have 2 genes that determine the blood type of their offspring. Each parent shares only 1 of their 2 genes with their offspring. The dominate gene determines the offspring’s blood type. I’ve been out of college for a long time. I didn’t have much science in college, but I’m making up for it now. Enjoyed your article very much. Genetics is so very interesting. Thank you for sharing. : )

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  109. now confused over bloodtyping

    ok, my first husband was O+ and so am I , our child is O-, my second husband is A+, me O+ and our child is A-… how is this?

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    • kim

      You = O + – (positive is the dominant gene and negative recessive)

      First husband same.

      You both gave your recessive gene to your child.

      Second husband will have to be A+ –

      Your second child will be AO blood type (A being the dominant and O recessive) and like your first husband you both gave your recessive – to your child.

      Hope this helps.

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  110. Jacqueline Gardiner

    I remember talking with ny genetics instructor about this. Both my parents are rh positive. My Dad had issue believing I was his because I’m rh negative. Initially she said no, its not possible for two positives to have a negative. My heart fell through my stomach. As I turned to walk away she yelled “wait a minute!” I learned that one of them carries the recessive gene. Pretty cool stuff.

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  111. Ravi Bhatia

    my son is ab positive , me & my wife are both b positive. is it possible?

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    • Cody

      I don’t think so. To have a b type blood you have to have two genes that are either BB or Bo. If two people make a baby that have B type blood it is either BB+BB or Bo+BB or BB+Bo or Bo +Bo. There is no A in the mix to make AB child.

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  112. kat

    Okay, my parents are rh+ both of them. what would i be?

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  113. april

    My blood type is B- HR what would my parents blood types be?
    I have 2 kids and they both have AB+, I was given the rhogam shot during and after both my
    prengnecies, why?

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  114. Chris

    Please help…. I’m confused,.. My blood type is B positive and my mothers is A negative, is this possible ?

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    • Michelle Patterson

      Yes. Your father must have been B positive. Everyone actually has TWO letters (one from each parent) and TWO Rh signs. So since you are B+ you are either BO++ or BO+- (BB++ or BB + – would also be type B+ but that can’t be you, because of your mother she had no B to give you or it would show in her blood type. ) Your mother, being A- is actually either AO– or AA– She could have given you the O. Obviously she didnt give you a B, which is why you are BO not BB.) If she had given you the A you would be type AB. So she gave you the O. She definitely gave you the – since she only has – – . So she gave you O – and your father must have given you B+ which means you are BO+- which would be interpreted as type B+

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  115. anne

    helloo,i had a question pls kindly give me an answer .Is it normal that the father ,mother ,and a daughter had same blood types?coz one of my friend family they had all O POSITIVE blood types.

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  116. Emma Lane Davis

    i am in my first pregnancy and my blood type is A- and i have Rh- blood yet my mother has A+ and my Dad has O+ and they are both Rh+. my dr tested my blood thats how i know i’m A- and Rh-. but i don’t understand how this is my blood type and my parents are both positive.

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    • Cody

      For you to have A- blood your parents would both have to have receive Rh-. So your mom could have AA+- or Ao+- and your dad would have oo+- .

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  117. jayson

    hi my parents are both os and i’m ab are they my really parents?

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    • Marisol Torres

      I am a mom that has O- and my husband has O+, both of the kids that I gave birth to are AB+ Even though teachers have asked our kids if they were adopted, my kids know they were not adopted. So it is possible! I guess rare, but possible ;)

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      • jayson

        thank you :)

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        • Marisol Torres

          You are welcome!

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  118. Julie Balfour

    My mum is 0+ I am 0- what blood type could my father be?

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    • Kezia Elizabeth

      B, A or O positive or negative

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  119. Joanne Jackson

    My mother is B I don’t. Know positve or negative my dad is a postive but I always thought my step dad which is o postive was my dad is it possible?

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  120. Heather Hylemon

    I have a question both my parents are o blood type but im a+ an my sister is o as well how is that possible

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  121. Stephen Maria Jarrells

    My dad is an O- my mom is an O+ but I am absolutely B- Rh-…does anyone have an answer? My mom refuses to talk & unsure what hospital i was born my dad says he’s my dad and dont mind a blood test. Plz help

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  122. lorraine wallace

    I am o negative reh both my parents are b+ how is this possibly. ???

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    • Cody

      O and Rh- are recessive genes. Even if someone has them it will not show in their blood type unless they have both of them. So your parents would have to be Bo+- for you to be oo– which is O-.

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  123. Jannette Davidson

    Both my parents are O+, so are all my siblings. I am A+ and my mother swears she never had an affair. I also have very dark skin, no widow peak, and unattached earlobes. Please figure that one out.

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    • Here is more information for you from Dr. Greene –http://www.drgreene.com/unders… One thing to to consider, your blood type could be an error. Before you go any further, consider having your blood type re-tested.

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      • Jannette Davidson

        I am sure my blood type is correct. I don’t think the U.S. Army, the V.A. hospital and all the times I have donated blood could be wrong. We all know out blood type from getting tested when my grandpa and step dad needed to find a match for kidney disease. From what I gather there is a thing called a genetic mutation, can this be the cause?

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        • I don’t know if it could be genetic mutation. That’s a great question. Does anyone else here know?

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          • R Quispe

            According to the following website there is still a very very small possibility of genetic mutation

            http://genetics.thetech.org/ask/ask181

            However, if you are still unsure, only a DNA test will give you peace of mind.

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  124. desteny

    I have a question my sister had her period on novrmber 8 on the 14 she have relationship with one man on december 11 she was in another relation with someone else in january she found out she was pregnant acording to the doctor she consive on december 27 and her due date september 19 she had the baby premature she is A positive the father is Rh o positive and the baby is o positive can that happen

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  125. april

    Hi there,
    Me and my sister are 1yr. and exactly 18 days apart same mom and dad. We have blood type RH O negative and we both have to take the RohGam shot. Now I was told by an RN that it’s impossible for us to be from the same parents and have this blood type. That only one child will come out with RH O negative. Is this true???

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  126. Me Trost

    Question: I am Blood Type O+ and my Brother is Type A+. What Blood Type combination(s) would our parents (RIP) have to of had for me (Sister) to be O+ and Brother to be A+?

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  127. Noelito Zipagan Glorial

    pls answer, how about parents with O type, and the child is A??is this possible??pls answer

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  128. Rose

    I am A-, my sister is A+, my brother is O+………is it possible that we have the same mother and father? There are doubts that we have the same father. We think we have the same mother but our father is the ?

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  129. Cheryl Boisoneault

    I am RH-A negative . My Mom is O positive and my Dad is B positive …How did this happen?

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  130. rj

    hi good eve. i have a question regarding my blood type my parent is A blood type me is B negative is it really my parent

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  131. Mohammed Mubeen

    Hi, i hav a question that my blood group is AB and Rh positive and my wife is O+ and Rh negative so what will be the result for this…?? and if she has O= and Rh positive then what will be the result…??????

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  132. Miranda Decker

    Here’s an odd one. My parents are both o+, so is my sister… I am A negative. So… I’m really starting to wonder how this would be possible….

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    • Cheryl Boisoneault

      Same here did you get an answer? my parents are positive to and both my brothers as well None have A blood…Or are they negative..my blood type is A negative RH ? I would love to know how this happened

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    • Mela

      My parents are both 0 + , me and my brother are 0 – . And its totally fine because 0+parents can only give birth to babies with 0+ or 0 – blood type. In our case it happened to be 0- . :)

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    • Charla Satterwhite

      Miranda, did you ever find the answer to your question? Because I need to know the same thing.

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      • mariya

        My blood group is a positive and my husband o positive. But our son o negative. Is it possible. ?

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        • Mariane

          I am A+ and my husband is O+ and our son is O- too. This is possible so don’t worry.

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  133. Miss Jennie

    My dad belongs to B type blood and my mom belongs to O type blood, whereas my brother belongs my dad’s blood type but how come my blood group is A positive?

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  134. Peggy Robinson

    Can a RH Negative and A O Have a A positive Child?

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  135. Peggy Robinson

    Can A RH Negative And a O Have an A positive child?

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  136. Miriam LuvEtte Saucedo

    My parents are both B+ … Why am i A+?

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    • Subasis Mishra

      Is it possible that baby having A+ve if both parents have B+Ve blood group?

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  137. Nean

    my mother has 0 Negative RH blood group – bit of confusion as my fathers dog tags of 1947 simply have 04 blood type…he told me they both have RH O Negative…and his is rare – I am O Positive – born in 1958 in an out back town in the Northern Territory where blood transfusions for the baby be non existent…very confused…my younger brother definitely theirs RH factor child severe anger issues, learning difficulties speech, tactile…I am 55…my parents told me I was adopted they are both in their late 80’s and with cancer I am their carer mum is now in full time care…could you please tell me is it possible for two O negative Rh blood groups to have children…my brother is fine now but was an out of control toddler and child and violent…thanks so much they do not wish to discuss my adoption which is fair enough.

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  138. island boy

    Hello, I have a question. Can both parents with type O blood produce a type A+ child? Both my parents are type O and i am type A+. Switches in the hospital can happen to where i am coming from. Please help!

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    • Huckle_Cat

      I think he answered this question in the paragraph where he says, “if two parents both have type O blood, all of their children will have type O blood.” That is because they can only pass on a type O gene to their children.

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    • Jaclyn Elaine

      My parents are both o+, and me and my twin sister are ab+ so we have been wondering this as well. There is no question of paternity or switching at birth as we are splitting images of our parents, and we are pretty confident in the results of the blood tests

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    • Michelle Patterson

      No. If both of your parents are type 0, they could NOT produce a type A child.
      It is possible that either one of the three of you is incorrect about your blood type. It is still possible they are both your parents if either of the three of you is incorrect about your blood type. Or possibly one of them is not your parent. If you are 100% certain you are type A then you HAD to get that A from one of your biological parents, either your father or mother. Your mother could be type O, but then your father would have to be type A, or vice versa

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