It also has a role in the treatment of chronic bronchitis, traveler's diarrhea, shigella, and in both the treatment and prevention of pneumocystis carinii pneumonia.
Most bacteria must manufacture their own supply of folic acid or folate. Animals (and some bacteria) depend on outside sources of folic acid, getting what they need from what they eat. Trimethoprim and sulfamethoxazole are both compounds that block the internal production of folic acid. Thus these compounds are relatively safe for humans, yet lethal to many bacteria.
The sulfamethoxazole component of Septra is a sulfa (or sulfur containing) drug. It causes fewer side effects than the other sulfa drugs, but its side effects should be respected.
The most common significant adverse effects are allergic skin reactions. Most of these are mild, but occasionally they are quite severe. Septra should be discontinued at the first sign of a skin rash.
Excess sun exposure should be avoided by anyone taking Septra.
Sulfa drugs may precipitate in the urine, producing crystals that can cause bleeding, urinary obstruction, or kidney damage. This is best prevented by using the most soluble of the more than 150 different sulfa drugs (such as the sulfamethoxazole in Septra) and by drinking lots of fluids while on the medication.
Allergic kidney damage can also occur, underscoring the need to stop taking Septra at the first signs of an allergic skin rash. When Septra is used on an ongoing basis, occasional blood and urine testing (a urinalysis, CBC, BUN, and creatinine) can detect early signs of problems.
Septra should not be used in children with folate deficiency.
Septra interacts with Dilantin, with methotrexate, and with anticoagulant medications; it should be used cautiously if these other drugs are being taken.
Dear Dr. Greene, After eight months of nursing, I contracted a breast infection. I called my OB's office and spoke with the on-call nurse. I told her my symptoms, she prescribed antibiotics and told me it was safe to continue nursing my son. I have two questions - Is there anything I can do, besides taking the antibiotics, that will help speed my recovery? How can I avoid getting another one? I want to keep nursing, but this really hurts!
San Mateo, California
First of all, may I say that I applaud your efforts to continue nursing your baby, even when it is painful. Nursing has a powerful, positive impact on a baby's health. By the time your baby is eight months old, he has undoubtedly begun eating a wide variety of solid foods. Even so, he continues to gain a large portion of the nutrition he needs from your breast milk. In addition, his immune system will be developing particularly rapidly until he reaches about one year of age. Until that time his own, immature, immune system is greatly augmented by the immunoglobulins he receives from your milk.
Breast infections are most common in the period from two to six weeks after birth, but they can happen as long as you are nursing. They are caused by bacteria that normally live on the surface of the breast, and may be complicated by a clogged milk duct. In many cases they are quite painful, and can be accompanied by flu-like symptoms. They are nothing to take lightly! Here are some suggestions for speeding your recovery:
Get lots of rest. Don't wait until you are forced to go to bed! Start immediately.
Drink at least eight glasses of water a day. The kidneys are an incredible filter and help to clean the infection out of your system.
Place moist hot packs on your breasts. This stimulates blood flow to the infected area, which is another way the body has of healing itself.
Nurse from the infected breast first. You should do this because often the second breast is not fully emptied. Emptying the breast helps speed recovery by keeping fresh milk flowing through the breast. If you do not feel like the breast is empty, pump after each feeding.
Wear a good nursing bra that fits properly. It should offer support without restricting circulation.
Transient breast lumps are often present during breast infections. If a lump persists, don't take it lightly! Breast cancer is not common in nursing women, but when present it is commonly missed.
Get proper nutrition and continue taking prenatal vitamins. Your overall health is essential in the healing process.
Take the full course of antibiotics recommended by your physician. If you truly have mastitis caused by bacteria, failure to take antibiotics can lead to worsening of the infection.
To minimize your chances of future breast infections, follow the general guidelines listed above and be sure to wash your hands thoroughly before you touch your breasts. It is very easy to go from a diaper change into nursing, but you must be very careful to wash your hands completely in-between.
No matter how many precautions you take, you may get another breast infection. The key to minimizing its effect is to treat early and aggressively! In other words, take good care of yourself. You are very important to your baby!!!
Most of the treatments for poison ivy, oak and sumac are aimed at reducing the itching, until the self-limited rash runs its course, which takes about two weeks. Click here for Dr. Greene’s tips on treating these allergic reactions.
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