Trisomy 13

Alternative Names

Patau syndrome

Definition of Trisomy 13

Trisomy 13 (also called Patau syndrome) is a genetic disorder in which a person has three copies of genetic material from chromosome 13, instead of the usual two copies. Rarely, the extra material may be attached to another chromosome (translocation).

Causes, incidence, and risk factors

Trisomy 13 occurs when extra DNA from chromosome 13 appears in some or all of the body’s cells.

Signs and tests

The infant may have a single umbilical artery at birth. There are often signs of , such as:

Treatment

Treatment of children with Trisomy 13 is planned on a case-by-case basis. The type of treatment given depends on the patient’s individual condition.

Expectations (prognosis)

The syndrome involves multiple abnormalities, many of which are not compatible with life. More than 80% of children with trisomy 13 die in the first month.

Review

Diana Chambers, MS, EdD, Certified Genetics Counselor (ABMG), Charter Member of the ABGC, University of Tennessee, Memphis. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 8/11/2009

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