Alternative Names
Reiter syndrome; Post-infectious arthritis
Definition of Reactive arthritis
Reactive arthritis is a group of inflammatory conditions that involves the joints, urethra, and eyes. There may also be sores (lesions) on the skin and mucus membranes.
Causes, incidence, and risk factors
The exact cause of reactive arthritis is unknown. It occurs most commonly in men before the age of 40. It may follow an infection with Chlamydia, Campylobacter, Salmonella, or Yersinia. Certain genes may make you more prone to the syndrome.
Symptoms
Urinary symptoms usually appear within days or weeks of an infection. Low-grade fever, inflammation of the conjunctiva of the eye (conjunctivitis), and arthritis develop over the next several weeks. The arthritis may be mild or severe, and may affect only one side of the body or more than one joint.
Signs and tests
The diagnosis is based on symptoms. Since the symptoms may occur at different times, the diagnosis may be delayed. A physical examination may reveal conjunctivitis or typical skin lesions.
Treatment
The goal of treatment is to relieve symptoms and treat any underlying infection.
Expectations (prognosis)
Reactive arthritis may go away in a few weeks, but can last for a few months. Symptoms may return over a period of several years in up to half of the people affected. The condition may become chronic.
Review
Mark James Borigini, MD, Rheumatologist in the Washington, DC Metro area. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 5/13/2010
