Pulmonary veno-occlusive disease

Alternative Names

Pulmonary vaso-occlusive disease

Definition of Pulmonary veno-occlusive disease

Pulmonary veno-occlusive disease is an extremely rare form of high blood pressure in the lung area.

Causes, incidence, and risk factors

In most cases, the cause of pulmonary veno-occlusive disease is unknown. The condition may be related to a viral infection. It may occur as a complication of certain diseases such as lupus, or as a complication of leukemia, lymphoma, chemotherapy, or bone marrow transplantation.

Signs and tests

The doctor will perform a physical exam.

Treatment

There is currently no known effective medical treatment. However, the following medications may be helpful for some patients:

Expectations (prognosis)

The outcome is often very poor in infants with a survival rate of just a few weeks. Survival may be months to a few years in adults.

Review

David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 6/2/2010

Respiratory system

ADAM Medical Encyclopedia

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