Alternative Names
Shy-Drager syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson’s plus syndrome; MSA-P; MSA-C
Definition of Multiple system atrophy
Multiple system atrophy (MSA) is a rare condition that causes symptoms similar to . However, patients with MSA have more widespread damage to the part of the nervous system that controls important functions such as heart rate, blood pressure, and sweating.
Causes, incidence, and risk factors
The cause is unknown. MSA develops gradually and is most often diagnosed in men older than 60.
Symptoms
MSA damages the nervous system, which can cause the following symptoms:
Signs and tests
The health care provider may perform the following:
Treatment
There is no cure for MSA, and there is no known way to prevent the disease from getting worse. The goal of treatment is to control symptoms.
Expectations (prognosis)
The outcome is poor. Loss of mental and physical functions slowly get worse. . Early death is likely. The typical survival time from the time of diagnosis is 7 to 9 years.
Review
Kevin Sheth, MD, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 11/22/2010









