Mononeuritis multiplex

Alternative Names

Mononeuropathy multiplex; Multifocal neuropathy; Peripheral neuropathy – mononeuritis multiplex

Definition of Mononeuritis multiplex

Mononeuritis multiplex is a nervous system disorder that involves damage to at least two separate nerve areas.

Causes, incidence, and risk factors

Mononeuritis multiplex is a form of damage to one or more peripheral nerves — the nerves outside the brain and spinal cord. It is a group of symptoms (syndrome), not a disease.


Symptoms will depend on the specific nerves involved, and may include:

Signs and tests

A detailed history is needed to determine the possible cause of the disorder. Examination and neuromuscular testing may show a loss of feeling and movement due to problems with specific nerves. Reflexes may be abnormal.


The goals of treatment are to:

Expectations (prognosis)

If the cause can be found and successfully treated, and if damage is limited, a full recovery is possible. The amount of disability can range from no disability, to partial or complete loss of movement, function, or sensation.


Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 9/13/2010

Central nervous system

ADAM Medical Encyclopedia

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