Gonadotropin deficiency; Secondary hypogonadism; Kallmann syndrome
Definition of Hypogonadotropic hypogonadism
Hypogonadotropic hypogonadism is absent or decreased function of the male testes or the female ovaries. It is considered a form of secondary hypogonadism, which means the condition is due to a problem with the pituitary or hypothalamus gland.
Causes, incidence, and risk factors
Hypogonadotropic hypogonadism is caused by a lack of the gonadal stimulating pituitary hormones: follicle stimulating hormone (FSH) and luteinizing hormone (LH).
Signs and tests
Tests that may be done include:
Treatment depends on the source of the problem but may involve:
With the right hormone treatment, the person can begin puberty and fertility may be restored.
Robert Cooper, MD, Endocrinology Specialist and Chief of Medicine, Holyoke Medical Center, Assistant Professor of Medicine, Tufts University School of Medicine, Boston, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 7/25/2009