Hypogonadotropic hypogonadism

Alternative Names

Gonadotropin deficiency; Secondary hypogonadism; Kallmann syndrome

Definition of Hypogonadotropic hypogonadism

Hypogonadotropic hypogonadism is absent or decreased function of the male testes or the female ovaries. It is considered a form of secondary hypogonadism, which means the condition is due to a problem with the pituitary or hypothalamus gland.

Causes, incidence, and risk factors

Hypogonadotropic hypogonadism is caused by a lack of the gonadal stimulating pituitary hormones: follicle stimulating hormone (FSH) and luteinizing hormone (LH).

Signs and tests

Tests that may be done include:

Treatment

Treatment depends on the source of the problem but may involve:

Expectations (prognosis)

With the right hormone treatment, the person can begin puberty and fertility may be restored.

Review

Robert Cooper, MD, Endocrinology Specialist and Chief of Medicine, Holyoke Medical Center, Assistant Professor of Medicine, Tufts University School of Medicine, Boston, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 7/25/2009

Endocrine glands
The pituitary gland
Pituitary hormones

ADAM Medical Encyclopedia

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