Congenital platelet function defects

Alternative Names

Platelet storage pool disorder; Glanzmann’s thrombasthenia; Bernard-Soulier syndrome; Platelet function defects – congenital

Definition of Congenital platelet function defects

Congenital platelet function defects are problems with platelets, one of the blood elements needed for normal blood clotting. Congenital means present from birth.

Causes, incidence, and risk factors

Platelets are elements in the blood that help form clots. Congenital platelet function defects are that cause reduced platelet function, even though there are normal platelet counts.

Signs and tests

The following tests may be used to diagnose this condition:

Treatment

There is no specific treatment for these disorders.

Expectations (prognosis)

Treatment can usually control the bleeding. However, congenital platelet function defects are life-long conditions. There is no cure. Patients should take precautions to avoid bleeding.

Review

David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 3/2/2009

Blood clot formation
Blood clots

ADAM Medical Encyclopedia

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