B-cell lymphoma; High-grade B-cell lymphoma
Definition of Burkitt lymphoma
Burkitt lymphoma is a very fast growing form of .
Causes, incidence, and risk factors
Burkitt lymphoma was first discovered in children in certain parts of Africa, but it also occurs in the United States.
Burkitt lymphoma may first be noticed as a swelling of the lymph nodes (glands) in the neck, groin, or under the arm. These swollen lymph nodes are often painless, but can grow very rapidly.
Chemotherapy is used to treat this type of cancer. Commonly used medicines include prednisone, cyclophosphamide, ifosfamide, vincristine, cytarabine, doxorubicin, methotrexate, and etoposide.
More than half of those with Burkitt lymphoma can be cured with intensive chemotherapy. The cure rate may be lower if the cancer spreads to the bone marrow or spinal fluid.
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 9/6/2010