Acrodysostosis

Alternative Names

Arkless-Graham; Acrodysplasia; Maroteaux-Malamut

Definition of Acrodysostosis

Acrodysostosis is an extremely rare disorder that is present at birth (congenital). People with this condition have problems in the bones of the hands, feet, and nose, and mental retardation.

Causes, incidence, and risk factors

Most patients with acrodysostosis have no family history of the disease. However, sometimes the condition is passed down from parent to child. Parents with the condition have a 1 in 2 chance of passing the disorder to their children.

Signs and tests

A physical exam confirms this disorder.

Treatment

Treatment depends on the physical and mental problems that occur.

Expectations (prognosis)

Problems depend on the degree of skeletal involvement and . In general, patients do relatively well.

Review

Chad Haldeman-Englert, MD, Wake Forest University School of Medicine, Department of Pediatrics, Section on Medical Genetics, Winston-Salem, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. – 11/1/2010

Anterior skeletal anatomy

ADAM Medical Encyclopedia

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